Program | Bio-Manufacturing |

Optimization of fermentation/cell culture media: Explore next generation Technology, strategies and Innovation that improves Cell Culture Process Development to increase yield, reduce wastage and consistently produce high quality biological end product. Cell line development: Advancements in CHO Cell lines and expression systems for bioproduction and predominant cell lines, advantages/disadvantages of cell lines and cell banks, strategies for optimal bioprocessing. Process Development and Manufacturing evolution: Advances in Process Development and Manufacturing shaping the Future of ATMP development Facility design for continuous synigized biomanufacturing: Scaling down to decide which new technologies are relevant and which can be best applied as process intensification. Innovative monitoring, detection, measurement, control technology: Process analysis, optimisation and automation, improving efficiency and productivity at advancing critical stages. Identify optimal time- point of feeding, filtration and harvest.

Upstream Bioprocessing

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A compiling program that reflects key strategic issues that senior executives have identified

Intelligence that flourishes within Cell Gene Therapy communities.

Biological Manufacturing - Integrated Holistic Approach Proudly presenting the highly anticipated and exciting Bio-manufacturing 2024 Annual program; Comprised of fully renowned world class speaker and industry thought leaders. Following a comprehensive research process undertaken with an expert panel of advisory board and results from delegates surveys. The program is rich with robust content on innovation and pivotal breakthroughs; giving you insight on the latest industry trends and technologies impacting growth in the Biologics market. As Biopharma products are moving from niche to mainstream, the industry is facing a paradigm shift in cost, quality, complexity, and scale, creating opportunities to develop new and different technologies and operating models. Achieving the next phase of the industry potential will require a further revolution, not only in the laboratory but also in strategy, technology, and operations. Decisions made today will affect companies' competitive positions years or even decades into the future. Access the unparalleled wisdom of inside knowledge from leading companies such as Pfizer and GSK. Industry peers give presentations and case studies on success in overcoming key challenges and bottlenecks. Engage interactively with globally renowned leaders in round table group sessions and panel discussion. Key Topics of significants gains from deployment of technological innovation and techniques.

Strategies & Technology/ Quality, Compliance & Analytics

Facilities upgrades 4.0: Overcoming challenges with aging plants moving towards flexible manufacturing, automated processing and systems implementation. How ready is the industry for the tidal wave of biopharma demand?Navigating the Unique Manufacturing and Supply Chain Challenges in Commercializing Cell and Gene Therapy Staying Ahead of the Curve in an Increasingly Complex Regulatory World: Establishing a quality mindset across manufacturing and operations Examining the cost of compliance and striking a careful balance between quality and cost management Preventing product variation and maintaining quality: Risk management strategies Monitoring Aggregation, Characterisation, Stability and Quatification. Single-use systems key technologies and considerations: Designing an integrated fluid handling systems. Improve efficiency and cost through flexible, knowledge based approaches.

• Downstream Process Development: Global Strategy to Enrich Full Capsids in Adeno-associated Viral Vector Based Gene Therapy. • New developments in chromatography: How will this shape the future of protein purification? Bridging the gap between the structure of purified proteins and their function in a cellular context. • Advancs in Recovery and purification: Leveraging technology innovation to overcome the direct impact of high titer processes In downstream processing. • New virus and pathogen clearance and safety in biologics Achieving greater assurance on viral clearance for more complicated products. Risk Assessment and management, design, Evaluation, and Characterisation of Procedures. • The future of downstream processing: Overcoming current challenges in developing Purification Platforms to alleviate Bottlenecks

Larry Sun Director of Upstream Amgen

Lada Laenen, Sc.D. VP Global Head Manufacturing Sciences and Technology GSK

Micheal Washabaough CSO AdelloBio

Firelli Alonso-Caplen, PhD Senior Director, Biotherapeutics & Vaccines Outsourcing Pfizer

Dr Alain Bernard VP Tech Operations UCB

“Learn, Debate And Bench Mark With Some Of The Most Influential Leaders In Bio Manufacturing Globally”

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